How do I specify different Layouts in the ASP.NET MVC 3 razor ViewStart file?

You could put a _ViewStart.cshtml file inside the /Views/Public folder which would override the default one in the /Views folder and specify the desired layout:

@{
    Layout = "~/Views/Shared/_PublicLayout.cshtml";
}

By analogy you could put another _ViewStart.cshtml file inside the /Views/Staff folder with:

@{
    Layout = "~/Views/Shared/_StaffLayout.cshtml";
}

You could also specify which layout should be used when returning a view inside a controller action but that's per action:

return View("Index", "~/Views/Shared/_StaffLayout.cshtml", someViewModel);

Yet another possibility is a custom action filter which would override the layout. As you can see many possibilities to achieve this. Up to you to choose which one fits best in your scenario.

UPDATE:

As requested in the comments section here's an example of an action filter which would choose a master page:

public class LayoutInjecterAttribute : ActionFilterAttribute
{
    private readonly string _masterName;
    public LayoutInjecterAttribute(string masterName)
    {
        _masterName = masterName;
    }

    public override void OnActionExecuted(ActionExecutedContext filterContext)
    {
        base.OnActionExecuted(filterContext);
        var result = filterContext.Result as ViewResult;
        if (result != null)
        {
            result.MasterName = _masterName;
        }
    }
}

and then decorate a controller or an action with this custom attribute specifying the layout you want:

[LayoutInjecter("_PublicLayout")]
public ActionResult Index()
{
    return View();
}

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One more method is to Define the Layout inside the View:

   @{
    Layout = "~/Views/Shared/_MyAdminLayout.cshtml";
    }

More Ways to do, can be found here, hope this helps someone.

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This method is the simplest way for beginners to control Layouts rendering in your ASP.NET MVC application. We can identify the controller and render the Layouts as par controller, to do this we can write our code in _ViewStart file in the root directory of the Views folder. Following is an example shows how it can be done.

@{
    var controller = HttpContext.Current.Request.RequestContext.RouteData.Values["Controller"].ToString();
    string cLayout = "";

    if (controller == "Webmaster")
        cLayout = "~/Views/Shared/_WebmasterLayout.cshtml";
    else
        cLayout = "~/Views/Shared/_Layout.cshtml";
    
    Layout = cLayout;
}

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