Is it possible to use global variables in Rust?

It's possible, but heap allocation is not allowed directly. Heap allocation is performed at runtime. Here are a few examples:

static SOME_INT: i32 = 5;
static SOME_STR: &'static str = "A static string";
static SOME_STRUCT: MyStruct = MyStruct {
    number: 10,
    string: "Some string",
};
static mut db: Option<sqlite::Connection> = None;

fn main() {
    println!("{}", SOME_INT);
    println!("{}", SOME_STR);
    println!("{}", SOME_STRUCT.number);
    println!("{}", SOME_STRUCT.string);

    unsafe {
        db = Some(open_database());
    }
}

struct MyStruct {
    number: i32,
    string: &'static str,
}

You can use static variables fairly easily as long as they are thread-local.

The downside is that the object will not be visible to other threads your program might spawn. The upside is that unlike truly global state, it is entirely safe and is not a pain to use - true global state is a massive pain in any language. Here's an example:

extern mod sqlite;

use std::cell::RefCell;

thread_local!(static ODB: RefCell<sqlite::database::Database> = RefCell::new(sqlite::open("test.db"));

fn main() {
    ODB.with(|odb_cell| {
        let odb = odb_cell.borrow_mut();
        // code that uses odb goes here
    });
}

Here we create a thread-local static variable and then use it in a function. Note that it is static and immutable; this means that the address at which it resides is immutable, but thanks to RefCell the value itself will be mutable.

Unlike regular static, in thread-local!(static ...) you can create pretty much arbitrary objects, including those that require heap allocations for initialization such as Vec, HashMap and others.

If you cannot initialize the value right away, e.g. it depends on user input, you may also have to throw Option in there, in which case accessing it gets a bit unwieldy:

extern mod sqlite;

use std::cell::RefCell;

thread_local!(static ODB: RefCell<Option<sqlite::database::Database>> = RefCell::New(None));

fn main() {
    ODB.with(|odb_cell| {
        // assumes the value has already been initialized, panics otherwise
        let odb = odb_cell.borrow_mut().as_mut().unwrap();
        // code that uses odb goes here
    });
}

Look at the const and static section of the Rust book.

You can use something like the following:

const N: i32 = 5;

or

static N: i32 = 5;

in the global space.

But these are not mutable. For mutability, you could use something like:

static mut N: i32 = 5;

Then reference them like:

unsafe {
    N += 1;

    println!("N: {}", N);
}

I am new to Rust, but this solution seems to work:

#[macro_use]
extern crate lazy_static;

use std::sync::{Arc, Mutex};

lazy_static! {
    static ref GLOBAL: Arc<Mutex<GlobalType> =
        Arc::new(Mutex::new(GlobalType::new()));
}

Another solution is to declare a crossbeam channel transmit/receive pair as an immutable global variable. The channel should be bounded and can only hold one element. When you initialize the global variable, push the global instance into the channel. When using the global variable, pop the channel to acquire it and push it back when done using it.

Both solutions should provide a safe approach to using global variables.

Heap allocations are possible for static variables if you use the lazy_static macro as seen in the documentation:

Using this macro, it is possible to have statics that require code to be executed at runtime in order to be initialized. This includes anything requiring heap allocations, like vectors or hash maps, as well as anything that requires function calls to be computed.

// Declares a lazily evaluated constant HashMap. The HashMap will be evaluated once and
// stored behind a global static reference.

use lazy_static::lazy_static;
use std::collections::HashMap;

lazy_static! {
    static ref PRIVILEGES: HashMap<&'static str, Vec<&'static str>> = {
        let mut map = HashMap::new();
        map.insert("James", vec!["user", "admin"]);
        map.insert("Jim", vec!["user"]);
        map
    };
}

fn show_access(name: &str) {
    let access = PRIVILEGES.get(name);
    println!("{}: {:?}", name, access);
}

fn main() {
    let access = PRIVILEGES.get("James");
    println!("James: {:?}", access);

    show_access("Jim");
}

Use crate once_cell or lazy_static, or SyncOnceCell in nightly.